EXPLAINER: Lab results and their interpretation

As @chul_chan mentions, there are multiple potential causes for this discomfort and it does not necessarily mean it is due to Hepatitis B. There is an ongoing discussion about this in other threads: Upper right quadrant pain.

Perhaps some @PharmacyExperts can provide some input here?

Thomas

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Thank you Dr. Thomas Tu I am impatiently waiting for their contribution. I can’t stop phenobarbital because I will see the crisis again. But since I started this treatment, there is no epileptic seizure. The seizures that I often had are when I sleep.

If I share a little my situation before I started the crisis, when I sleep at night, my brain does not sleep (that is to say my body sleeps but my brain is on standby). and when I get up in the morning, I am like a tired person, I have headaches and also I want to go back to sleep. if you have any advice, give me, I will share with my neurologist.

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No I didn’t take it valporate. @chul_chan

No, you should not make any changes regarding your long term medications without consulting with your doctor first.

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Hi everyone.
I am a male, 38 years old from Europe. Last year, I found out that I have chronic hepatitis b. Since then, I go for a blood work every 3 months plus Ultrasound. I also quit drinking and start to eat quite healthy since my diagnosis.
When you find time, could you please explain to me my lab results. According to my doctor at this point I don’t need treatment, something does not give me peace, and will be very appreciate if you give me some advice do I need to push for a treatment. As I said I am with chronic hepatitis b, with HBeAg-negative.
First result HBV-DNA 240 iu/ml
Second - 2000
Third - 3300
Fourth - 3100
Fifth - 1800
Last one-1100
ASAT and ALT in normal range (around 20,25)
CT showed light Steatosis. Elastography - light. Ultrasound only a little fatty liver.
My doctor will not recommended treatment at this point, do you think that this is a best option? I actually don’t know since when I am infected.
Will be very appreciate for some advice!!!

Thanks in advance!

Hello i have a question can someone help me understand my results i am 24yr old got vaccinated as a child.

HBsag Non reactive
HBsab Reactive

Tested at another clinic

HBsab: 9.69mIU
HBsag: Non reactive
HB Core Antibody: Non reactive

Hi @ka85,
Welcome to the community. Based on the results you have shared, I have to agree with your doctor about not starting treatment yet. Your HBV DNA is not that high and actually seems to be coming down. The continued monitoring is important as things might change down the road and treatment will be required. But currently, I don’t think a treatment is warranted based on your test results. Best, Bansah1

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Hi @Carlos_Gomez,
Welcome to the community and thanks for your question. Your labs indicate that you do not have hepatitis B (HBsAg negative/non-reactive), you have protection or antibodies against HBV which is great (HBsAb positive/reactive). No vaccination is required and you are good. I hope this is helpful, Bansah1

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Hi Bansah1. I really want to thank you for your time and responding to my question. I will continue make blood tests on every 3 months. I had read, that viral load above 2000 and elevated enzymes required treatment. But actually my enzymes are in normal range, and my viral load were just two times above 2000, and now I am a bit confused. I also check my Afp and was 3,2. Do you think that my results are more likely like inactive carrier?
Regards.

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You bet. So the new guidelines say HBV DNA of 2000, which you seem to be hovering around but your LFTs and imaging are normal. With just the viral load below 2000, treatment is not required. Unless you have a family history of HCC or a dramatic change in these numbers then I can see the need for treatment. AFP of 3.2 is still considered normal. AFP less than 6 is good. Higher than 6 then there is a concern. The lack of stability in your numbers tells me it is possible to have an active case. It can also be an inactive case with just flare-ups as indicated by viral load fluctuations. It is hard to say exactly. Keep up with your monitoring and continue doing whatever you have been doing. Thanks, Bansah1

Thanks one more time for your answers, I appreciate it!
This sentence from you “Afp 3,2 is still considered normal” can not give me peace somehow. I thought that 3,2 is like very good result :roll_eyes:
Yes, I will continue monitoring!!!

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You are right, it’s a good result. That’s why I mentioned that overall anything less than 6 is good. Thanks, Bansah1

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Can someone explain this test result please

Hi @Richlove,
It is hard to see what the T shows across. Check on the package and it should have a guide on how to read the test results. It is difficult to tell from what you have shared. Bansah1

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@Bansah1 thank you for your response will definitely check it out please

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Hello, can someone help my understand what this means?

Ag DE SUPERFICIE HEPATITIS B (Ag.HBs) → NEGATIVE
Ac ANTI-ANTIGENO DE SUP VHB(HBsAc) → 24.10 mUI/ml POSITIVE
Ac IgG ANTI-CORE HEPATITIS B NEGATIVE

Hi @ test_user
Welcome to hepbcommunity.org forum .
Your laboratory results show that HBsAg -ve and anti HBc -ve which mean that you have no HBV exposure or infection and you have anti HBsAg +ve = 24.10 mIU/ml which mean that you have antibody produced by your body immune system to HBsAg due to vaccination and it can protect you from HBV infection, however, the antibody titer is quite low(<100 mIU/ml) and you should consult with your doctor to consider a booster dose of HBV vaccine to maintain the antibody titer at a protective level .I hope this nay help you.
chul_chan
Chulapong Chanta. MD. Pediatrics. CRH . Thailand.

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As @chul_chan points out, simply put: these results are consistent with someone who is protected from hep B and has never been exposed to it.

Thomas

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Thanks for your help

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