Let me remind each one of you all of freedom of speech.
A cured patient means losing a customer for the medicines. They dont care about you or me they care about youre wallet.
Past 15 years theyve been yapping about a cure (yh right) and no progress is made.
I mean past 2 years they send 100+ billion $ to ukraine, but hey no funds for a total cure? Hey man again they dont care lol. I lost my mind my life is ruined and doctors simply dont CARE. Im born in west europe been to hospitals and they are all clueless you know what they say? Shut up and take ur meds daily and get the **** out.
They give you a tiny bit hope for a “functional cure” in other words the virus is still present in your liver instead of doing slow damage…its gonna do ultra low damage untill your liver stops working.
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Calling for a total cure but they wont give it these people are sadists. Again they dont give a **** about you or me only youre €/$
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Dear @H020,
I respect your viewpoint and feel your frustration as well. I want to offer my perspective from being in the room where cures are discussed and the science around it is being developed for the last ~15 years, and also as a person with Hep B myself.
I have never seen anything untoward in terms of suppressing a cure or anything seeking profit over patients in any of my interactions with the scientific or medical community. None of us have come into the field seeking fortune (there are much much less frustrating ways to make money for the amount of training it takes compared to research). Both scientists and industry have poured a lot of effort, time, and money into trying to develop a cure (equivalent to hundreds of millions of dollars).
Just like every other research for treatments, we have found many ways that won’t cure Hep B during this time. But it’s untrue that no progress has been made. For example, we now have one of the first Hep B specific treatments getting out into phase 3 trials.
I wholeheartedly agree with you that there is not enough funds placed into the field relative to its impact. However, this has been an issue of governmental policy, rather than doctors (who are trying to address the health impacts directly on the ground).
I also agree that not every doctor is an expert in Hep B, particularly in Western Europe where Hep B is not common (compared to say South East Asia). Just like everyone else, doctors are trained and most comfortable working with issues that they see more often, and will often fallback to simply following the guidelines for conditions that are less common.
Finally, the existing antivirals do not make a huge profit for the companies who developed them, now that they are able to made as generics. The doctors also get no funding from prescribing these.
I’ve shifted this thread into “Get Involved” because I would like to see such frustration and anger being directed toward productive means. To some extent, there is a need to being upset about injustices and drive awareness of this issue to those controlling the resources.
I hope this contextualises some things,
Thomas
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It’s not about freedom of speech, no one bans negative thoughts. But what was the reason of your post ? If you live in western world you’ve got better treatment and overall live conditions
than 90% of all people around the world. Appreciate it.
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Hi @H020,
While I understand your frustration and anger, please let us leave Ukraine out of this. Ukraine is not the reason why there has not been a cure for HBV. Besides, the majority of the funding announced for Ukraine actually doesn’t go to Ukraine. They are military aid and the money is used to replace the weapons we don’t need because they are old and ineffective that are given to Ukraine. The majority of this funding is used to rebuild those supplies. The military manufacturing complex are the ones getting the largest chunk of all those monies and not Ukraine.
Let’s not drag a country that is fighting daily for its survival, existence, and culture into why there is no cure for HBV. Maybe we should blame the people we continue to vote for or elect who don’t seem to care about us. They only care about staying in power and the next election.
Freedom of speech does not mean being inaccurate with facts or falsely accusing others. We can all do better. Best, Bansah1
Thing about all the people that had HCV prior to 2013. They probably felt the same way. But alas, Pharmasset developed a cure for it. The same thing may happen. Theres a ton of trials out there going on right now using different modalities. It takes a while for these and things get discovered along the way. They thought SiRNA was the answer until they found out that SIRNA by itself isnt enough and they would need to combine it with other methods. And I do remember reading from a medical journal that finding a “functional cure” actually puts your chances of developing anything adverse very close to someone whos never been infected.
On another note to the experts, how do you feel about the Arbutus Biopharma SIRNA in combination with the VTP-300 therapeutic vaccine? They had preliminary results at EASL conference and it looks a little promising to me and im hopeful that at the AASLD conference they will have positive results from that trial in combination with Nivolumab. @sunnyban was talking about screening for that trial here last year. Hope hes doing great. Also how does the VTP-300 vaccine differ from the ThervacB vaccine that got a lot of chatter?
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