High Viral Load (Active Replication): Corresponds to a low Ct value (e.g., <25–30).
Low/Inactive Viral Load: Corresponds to a higher Ct value (e.g., >30–35).
You are positive for HepB and in active viral replication. You should followup with your doctor on additional tests and next step.
Thanks, Sir. But the doctor didn’t recommend any additional test and said I don’t need medication now.
@Abraham_A_Swaray Do you know if this is a recent (acute) infection, or is it chronic?
I am not a doctor. From your report, I understand that you are a 30-year-old from Liberia. Your viral load is measured to be 1250 iu/ml. This is not very high and is under 2,000 iu/ml. However, your ALT and AST are above normal, these are enzymes released by your liver cells or cells from other organs when they die or are damaged. Hepatitis B is a complicated and chronic disease, and whether you need treatment or not depends on many factors. I would suggest you consult an HBV specialist, and have a checkup at least every 6 months.
Hello
I would ask your Dr to check your platelet count, with AST and ALT can do special tests for liver fibrosis (APRI and FIB4). You may need treatment even if your viral load is low especially since your liver tests are also high. The WHO has simplified guidelines that recommend expanding treatment. Your Dr should check for other causes especially Hepatitis Delta Virus.
you have a liver disease…whether it’s HBV-related or not, that’s is another issue, your hepatologist will perform all the necessary examinaations
Hi, i am new user. i am also posting my results if anyone can suggest if it is acute or chronic or if someone had experience these kinds of numbers in the past. i happened to visit doctor for a stomach upset eason and since my ALT and AST looked high got into detail testing
hbsurface anti gen 1284
fibro scan 14.6 kpa
hbv viral load 338000000
alt reduced from 500 to 360 in 1 week
ast reduced from 287 to 230
hep b core antibody igm Reactive
hep be ag reactive
my doctor said nothing can be confirmed right now and we need to tests after few months to find out if it is acute or chronic…when i gogole these results it says chronic but this is the first time i have experienced the stomach discomfort.
Hello @pvnkv , welcome to the community. The positive core IgM would suggest that it’s acute, but it’s interesting that your Fibroscan score is so high, which is generally a sign of scarring on your liver. I’m not an expert, so I don’t know if it’s typical for an acute infection to cause that. I thought that liver fibrosis/cirrhosis generally occurred with long-term inflammation of the liver, slowly getting worse over many years, but I could be wrong.
I’m so sorry that this is scary and confusing for you. Maybe some @HealthExperts can weigh in?
Fibroscan does not measure fibrosis but stiffness…..thereby LSM is usually very high in patients with acute liver disease
Hi,
I recently got my tests done again, results are below
ALT REDUCED FROM 360 TO 235
AST REDUCED FROM 230 TO 155
HEP B CORE TOTAL AB REACTIVE
HEP B SURFACE ANTIBODY NON REACTIVE
HEP B SURFACE AB QUANTITATIVE <8.0
HBSAG REACTIVE
HEP B CORE ANTIBODY IGM REACTIVE
My doctor was still not sure if it is acute or chronic, he started me on tenvir af 25 mg keeping my HBV dna load which was taken 3 weeks before which showed 33 million
any interpretations from anyone, please advice!
Hi, Based on your Hep B Core IgM antibody, you likely have an acute infection. IgM antibody is produced early in HBV infection and is later replaced by IgG. I am not a doctor, but I think you should continue to monitor your HbsAg and anti-Hbsag antibody and your liver functions. I think it’s still possible you will clear the infection. Good luck!
Yes, agree with @Ace
TT