I’m very glad to find this community, the past few days were really difficult for me since I discovered that I have HBV infection, it was first discovered by a reactive Anti-HBc test, after consulting my gastroenterologist, he requested additional blood tests as follows.
Anti-HBc (total antibodies): Reactive (critical High)
HBs-Ag: Non Reactive
HBe-Ag: Non Reactive
HBV-DNA (PCR): Not detectable (95% rate of detection: 2,7 IU/ml (IU equivalent to 5,8 HBV genome copies)
Anti-HBc IgM: Non Reactive
Anti-HBs: >1000 mIU/ml (critical high)
Anti-HBe: Reactive (critical High)
Based on this, he said that I’ve developed full natural immunity from a past infection which is good, but my concern is that my Anti-HBe and Anti-HBs (> 1000) levels are critically high.
I wish someone can answer my question to better understand my current situation:
1- Does this indicate an over reaction from my immunity system against the virus that could lead to possible damage to liver cells?
2- or does it mean that I had several reactivations of the virus before that lead to this extremely high antibody levels?
3- in case for someone like me with + Abs, - Ag for the virus, is there still a change to acquire HDV, do I need to test for that?
4- how should I follow up my case in future, do I need to frequently test for HBV DNA or request additional tests to reduce the expected damage from the virus as much as possible?