New HBV Treatment Guidelines from APASL (Asia Pacific Liver Society)

HI all, I posted this on LinkedIn about the newly updated APASL guidelines: #apasl #hepatitisb #patientcentered #wholeperson #qualityoflife #patientpreference #treatall #shareddecisionmaking #stigma #transmission #mentalwellbeing #patientreportedoutcomes #qualityoflife #hepb… | Su Wang

Check out the new APASL guidelines!
APASL clinical practice guidelines on the management of chronic hepatitis B infection: a 2026 update - PubMed

A few #PatientCentered highlights that stand out to me:
:small_blue_diamond: Treating the #WholePerson, not just the liver: #QualityofLife is at the top of the treatment goal pyramid.
:small_blue_diamond: #PatientPreference: Inclusing into the treatment consideration algorithm.
:small_blue_diamond: #TreatAll: wherever resources allow, advocating for broad treatment initiation
:small_blue_diamond: #SharedDecisionMaking: Moving away from a purely clinical checklist to a collaborative approach.

The paragraph on the value of shared decision making is spot on: :bullseye:
“Shared decision-making improves adherence & addresses psychosocial burdens, such as #stigma, fear of #transmission, and treatment fatigue. Achieving viral suppression can improve #mentalwellbeing. For instance, one study showed a 4.5-point increase in SF-36 mental component score after one year of ETV therapy. While psychosocial improvement alone is not an indication for treatment initiation, these benefits underscore the broader value of antiviral therapy in enhancing #PatientReportedOutcomes and #QualityofLife.”

Kudos to the authors for being explicit about a patient-centered approach to #HepB Care!!:stethoscope::clap:

We now have updated HBV treatment guidelines from all the major liver societies (AASLD, EASL, Canadian) and WHO! Check out our article comparing them all

Shared principles within HBV guidelines: aligning clinical approach with differentiated care for global elimination - The Lancet Gastroenterology & Hepatology

8 Likes

Thanks @Suwang88 for posting this!

I think these new guidelines are a huge improvement! They largely achieve the treatment expansion goals that ICE-HBV was arguing for in our 2 “Evidence” papers (freely available at PubMed Central, ID numbers PMC12797741 and PMC7618342).

This is great news for people living with HBV!

John.

8 Likes