Hep B and Prednisone

I was prescribed Prednisone (20 mg for 5 days) to help with my clogged ear. My doctor suspects some inflammation of the Eustachian tube, trapping some fluid, therefore, Prednisone will help to reduce the inflammation.
I did some reading and was concerned about the fact that it can also suppress the immune system
My status is currently Inactive and I am concerned that any immune suppression, even for a few days could be detrimental to me.
Am i overreacting? Or can i take the medication.

Thank you.

Hello @Yaoman,

I’m sorry to hear about your sore ear. Ear aches can be so painful.
I’m not a doctor, but using medication for five days should be fine. Weighing up the benefits of getting your ear fixed. The ear is important to get fixed it can cause you to go deaf if it’s not treated and I know that as a fact because my mum and my sister both went deaf in one ear because they didn’t get a virus treated.
Hopefully the @ScienceExperts can help you soon.
Hope your ear clears up. And I haven’t scared you too much.


Thank you @Caraline for your encouraging and comforting words.

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You shouldn’t have a problem with your Hep B reactivating with being on 20 mg of prednisone for only 5 days.

I’ve been on prednisone since March 2022 due to an autoimmune inflammatory muscle disease that is called Polymyalgia Rheumatica that lasts about 5-6 years and am currently at 15 mg with no reactivation. In a couple of weeks I will start slowly reducing my daily dose with the hope I don’t experience any muscle pain in the process.

Dear @Yaoman,

Thanks for your question. 5 days is considered a short term of steroid therapy, and 20mgs is a relatively low dose. Low and short dosage are generally confer lower risk to reactivation. I’ll defer to @HealthExperts to provide you with more detailed information.

However, the best way to find out is talking to your doctor about your worries, because they are in the best place to integrate your medical history and your current condition to determine the best way forward.


Thank you @ThomasTu, @sloped876……your kind words has put my mind at ease.