How high does HBsAg level typically go during an acute (and eventually self-resolving) infection? Is there any data available on this?
Hi @mantana,
As far as I know, acute infections can still lead to the majority of the liver being infected (from chimpanzee studies where the dynamics of acute HBV infection could be recorded - https://journals.asm.org/doi/10.1128/jvi.77.1.68-76.2003), so I’d imagine the HBsAg levels would be similar ranges as chronic infection (10000-100). However, I don’t know if there’s if there’s a threshold that would predict clearance vs. chronic.
Cheers,
Thomas