My daughter, now 19, is in the pediatric TAF trial - she is known to have the actual drug for 1.5 years - possibley 2 (the first 6 months were blind). Her ALT/AST had gone to normal levels and her viral load is greatly reduced. With her draw last week, her ALT/AST and bilirubin have spiked. She continues to have the eAG and sAG along with no antibodies. As a college student, she has not been perfect about taking her meds.
What are the thoughts for this sudden flare? I am thinking she is either becoming resistant - though her viral load went down again, or hopefully trying to sero-convert the eAG.
I’d appreciate your thoughts and experiences! Karen