Dear @jazz,
This is great news for you as these results show that you have never been exposed to Hepatitis B. Given your anti-HBs antibody is not detectable, best practice would recommend that you should consider getting the HBV vaccine to protect you against any potential future exposure.
Hope this helps,
Thomas
Hello
It was a false positive then, thank you very much for the support. Good work team
Good afternoon,
Me again… I have now my daughter’s results. Could you please help me understand these?
Hep B surface Antibody level = Normal (on a chart on the app says 9.90)
Hep B surface antigen level = Normal / Not detected
Hep B core antibody level - Not detected
She has been vaccinated as a baby. Does she have immunity?
Thank you.
Hope
Hi @Hope2025,
9.9 is on the cusp of an antibody level that is considered protective, but it is likely that she functionally has immunity.
Hope this helsp,
Thomas
Hi Thomas,
Thank you so much for taking the time to reply to my message. I really appreciate this! Thank you for everything you do for this community. Although I didn’t write much here, since my husband has been diagnosed I have been reading a lot of posts and this helped me understand better a lot of things. I know that life is busy and even hectic sometimes, so taking the time to reply to so many messages is not easy. Thank you again!
Hope
@ThomasTu @Cornelius @Luis attached are my LFT results as of today.
I was diagnosed with Hep B 10 years ago and regularly seeing doctor and taking my entecavir. Can some check my lab results if I am functionally cured and no longer contagious?
Hi @Kr2025,
Welcome to the community. There is no evidence of seroconversion; however, your HBV DNA has been undetectable for many years, and your ALT/AST numbers are normal. While there is no evidence of a functional cure, your HBV looks well under control at least from these lab results. Keep doing what you are doing and remain in care. Best, Bansah1
Thank you for your response. I am still contagious being undetectable? What is seroconversion mean?
Dear @Kr2025,
Undetectable means aside from special cases (e.g, where you are giving ~1L of blood to someone), you cannot transmit to others in every day situations.
In this case, it means going from Hepatitis B Surface Antigen POSITIVE to NEGATIVE.
Thomas
Thank you, Thomas! 
I won’t say you are contagious, rather you are still infected. Given that your HBV DNA has been undetectable, that lowers the risk of infecting others with HBV.
Right now your surface antigen is still positive, but if you seroconvert that will become negative. So seroconversion is the condition where one improves from positive to negative. So if your surface antigen changes from positive to negative, we would say you have seroconverted. I hope this helps. Bansah1
I have been undetectable for over 7 years already, I’m still hoping that one day my surface antigen will be negative,… I wonder how though, I relatively live healthy…
Thanks for the response.
I hope that there will be a cure of Hep B in the next 5 years…
True. The majority of patients if managed well can live a healthy life. Keep up the good work. Continue to remain in care no matter what. Keep us updated whenever you can. Bansah1
Hi Tomas, is it safe for HEP B undetectable like me (while on Entecavir) to take take Prep as prevention for HIV?
Yes, you can take PrEP. If you take tenofovir-based PrEP, you may be able to discontinue entecavir, as tenofovir is also used to treat hep B and can achieve full viral suppression in most patients.
@Charles_Nsimbi Are you still taking medication? Your ALT is slightly elevated. I’d be curious to know what your HBV DNA is doing. Some fluctuations in ALT are to be expected. Mine usually fluctuates from being within normal range, to just above normal range, even on treatment. If you choose to stop treatment, there’s always a possibility that the virus can reactivate and start causing damage to your liver. If you have advanced fibrosis, cirrhosis, or a family history of liver cancer, it is strongly recommended for you to continue treatment until you reach a functional cure.
Thank you for your kind advice and response.
I began treatment(Tenofovir 300mg) in March for 6 months upon having a viral load of 4314 IU/ML.
After the 6 months(Oct), I had a viral of <20 IU/ML and LFTs as earlier shared, my doctor advised me to stop medication
And need to do follow up labs (Viral load and LFTs) every 3-6 months for atleast 1 year. Restarting will depend on those.
My family has no history of Liver cancer & cirrhosis.
Should I still continue with Tenofovir 300mg or I need to change my medication given the fact that I had a lapse of 3 months without taking medication.
It’s definitely not standard protocol to stop antivirals immediately after reaching undetectable viral load. What usually happens is that your viral load would go right back to where it was before. I myself took tenofovir for 3 years (2014-2017), and during that time, I went through e-antigen seroconversion. After I maintained that for 12 months, my doctor told me that I could try coming off treatment. I remained off treatment for 5 years and continued to be monitored every 6 months. After 5 years, my liver enzymes and HBV DNA started to go up again, so I restarted treatment. I would definitely recommend continuing to monitor closely, but if you do decide to start treatment again, there’s no indication that you would need to switch to a different medication.
Thanks for sharing your history.
I’ve noticed lots of people seem to think when they reach non detectable DNA, they think they can stop treatment.
I’m wondering if people are confusing HepB treatment with antibiotics!
I know in a very low number of people treatment can be stopped.
I myself would not want to take the risk. Also, the extra monitoring would be a hassle.
Easier to take one pill a day. My opinion only
