EXPLAINER: Lab results and their interpretation

Dear @Midnightstar,

Apologies that this post was missed, I did not get a notification as it was posted in another thread.

Yes, your viral load is relatively low - however to understand if you have liver injury because of the hepatitis B or not, you should have liver function tests (ALTs will tell you if there is active liver inflammation) and a fibroscan (this will show if you have past liver damage and scarring of the liver).

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Hi @Nick1,

These results are inconsistent as you have a positive hepatitis B surface Ag test but a negative anti-HBc antibody test. It may be best to get an additional blood test just to clarify what might be going on.

Hi @nolauser,

I’ve not heard of any impacts curcurmin has on blood test, so I don’t see any potential reason why these tests might be inaccurate. They are consistent with someone who has been vaccinated against HBV.

Hope this helps,

Thomas

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Hello everyone, I’m new to this group and I apologize if I don’t know the right way to post, so I’m writing here.

I was first diagnosed with hepatitis B in 2015 during a routine check‑up in Europe, in my home country. At that time, the doctor didn’t do any further tests and only advised me to check my liver enzymes once a year. I followed that advice, and every time my liver enzymes were normal.

In 2020, I decided to check more thoroughly, and my HBV DNA was 70 IU/mL. Since then, I only continued checking liver enzymes, which were always normal.

In June 2025, I finally saw a hepatologist. My HBV DNA was 80 IU/mL, and both ALT and AST were normal. At my annual exam with my primary care doctor in October 2025, liver enzymes were again normal.

On December 1, 2025, my HBV DNA was 103 IU/mL, and all blood work was in the normal range except ALT, which was 37 U/L (reference value 32).

I am still waiting for my hepatologist’s response, but I feel very anxious. I was considered an inactive carrier, and now I’m worried that my HBV might be reactivating. Is this mild ALT elevation related to the HBV DNA level, or is the HBV DNA just showing normal fluctuation rather than reactivation

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Hello, I had a hepatitis B test as part of investigations for my stomach and I just received test results that I don’t understand, and each doctor tells me something different:

HBsAg negative: value 0.2 ==> normal range <1

anti-HBc positive: value

Hello and welcome @Miya

Sorry I missed your post and extending your anxiety.

Our levels do fluctuate. Please don’t worry.

Listen to your health provider.

It’s great you have started to take care of yourself.

Have a read of some of our articles to help you understand more.

All questions are welcomed.

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Welcome and hello @jazz
I’m not an expert in lab results.
Someone will help you soon.
@banish @thomas

Hi @Miya,

Welcome to the forum and thank you for sharing your experiences.

At these low HBV DNA levels, it is unlikely that Hepatitis B is the cause of any increase in liver inflammation. To me, the HBV DNA level is not changing at all (they are all within the margin of error of the lab test), so reactivation would not be my first thought. As others have mentioned, there are other activities (including exercise) that can contribute to an increase in ALT.

Dear @jazz,

Welcome to the forum. I am not familiar with the actual units you have provided, but a positive anti-HBcAb and negative HBsAg is not a clear or classical profile. The anti-HBc Ab may indeed be a false positive. The only way to really know is to repeat the tests at a later date.

Hope this helps,

Thomas

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Hello, I had a Hepatitis B test as part of stomach analyses and I’ve just received results that I don’t understand, and each doctor tells me something different:

HBsAg negative: value 0.2 ==> reference range <1

Anti-HBc positive: value

hello dr,that is why i wroote to you,i got confused in tunisia ,each dr say sthing different ,here are the results, witch test i should repeat and how many days.

hello caraline I just found how to link my tests to the community, could you please request someone for further interpretation

thx

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hi thomas;I did some researchs in internet and i talk with many dr ,diagnostics change from person to person and the majority request and PCR ADN,but for me I ‘am really trying to move far ,ok I think it is possible to have a galse positive,do you advice to repeat all the tests or ony AC ANTIHBC?

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Hello @jazzJazz. I hope you have been answered. I’m not sure.

@ThomasTu @Bansah1

hi caraline,I’am very stressed from my result and i need that someone support me

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Hi @jazz,
Please refer to this response from @ThomasTu a few days ago regarding the test, and I agree with his assessment/recommendation. Thanks, Bansah1

Dear @jazz,

Welcome to the forum. I am not familiar with the actual units you have provided, but a positive anti-HBcAb and negative HBsAg is not a clear or classical profile. The anti-HBc Ab may indeed be a false positive. The only way to really know is to repeat the tests at a later date.

Hope this helps,

Thomas

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I have gone to the labor and he informed me that the technique used for test Elisa is always correct and the value couldn’t change,however he said i Need a PCR is it correct?

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Good evening,

My husband tested positive for Hep B a while ago (it is chronic). My daughter and I got tested and my results came back, but this is the only thing I can see on my patient app:

Hep B antigen level- NOT detected

Hep B core antibody level -NOT detected

Could you please help me understand this?

Also, my daughter has been vaccinated against Hep B first day after I gave birth. She is nearly 18 years old now. She has taken the same test as me. I expect her results to be different. If so. how would these results look like for her (of course, I have been praying that she doesn’t have the virus).

Thank you very much. One day, I will share our story with you. But at the moment, I can only say thank you so much for this forum, it helped me a lot.

Hope

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Hi @jazz,

There is no such thing as a test that is 100% correct. While it could be a false-positive anti-HBc result, there are also possibilities that you could have been exposed to HBV and it was in a time period before HBsAg was detectable, or it was in a time when you were clearing the infection and both HBsAg and anti-HBs were undetectable. Or some other scenario. In any case, the way to find out for certain is to repeat the anti-HBc, HBsAg, and anti-HBs tests.

Hi @Hope2025, this indicates that you have not been exposed to the virus. You would need to be tested for anti-HBs (surface) antibodies to determine if you are protected against the virus.

Your daughter should be positive for anti-HBs antibodies if she has responded well to the vaccine. This would indicate she is protected. Otherwise she should show the same test profile.

Hope this helps,

Thomas

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Hi Thomas,

Thank you very much! Does this mean that I don’t have the virus- chronic or viral?

Sorry, I would like to mention that these are the only two tests requested by my GP for both, my daughter and I: Hep B Core Antibody and Hep B Screen only.

Hope

Hi @Hope2025,

If the “Hep B antigen” is “Hepatitis B Surface antigen” in the tests you mention above, then that indicates that you do not have an infection (either acute or chronic).

A Hep B screen should include 3 tests: Hepatitis B Surface antigen, anti-surface antibody, and anti-core antibody.

Thomas

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hello dr , i repeated the antihbc test and now results are negatif..is it enough?