Please I need an interpreter for my result I have been vaccinated for hapitte B since 2021 to 2022 including 3 does I have done 2 medical test for fitness and I was fit
This year I went for another blood test and doctor said I have a reactive hapitte B of the following hbsag reactive, hbsab reactive, hbeag non reactive, hbeab reactive and hbcab reactive and Noone could explain to me and I’m dying thinking on what to do am confused just don’t know what to do now please any help
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Dear @Anthony_Oscar_Kamara,
Welcome to the forum and thank you for sharing your story. I understand that it is very stressful at the moment.
Being HBsAg-positive means you have a current infection of hepatitis B. You may have had this before your vaccination, which would have had no effect if you already had it. Hepatitis B is a manageable condition that many other people on this forum (including myself) have and live with.
It is important that you keep monitoring to: 1) confirm these blood results accurately reflect your condition; 2) to understand your liver health; and 3) to determine if you would benefit from treatment or if it is OK to just keep monitoring your condition for now.
Hope this helps,
Thomas
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Dr, am trying to do another test again but the country am currently is diffult to live with hapitte coz all test of it must knows by the government
Regarding my vaccination I did it 3yrs back even before my vaccination I want for a medical test which showed I am fit.
So that mean I was negative of it
Earlier this year I went home and doctor said I’m reactive of it. But like you said I will fight to redo the test again.
Hi @Anthony_Oscar_Kamara, I’m not sure about what the initial tests were and these do not necessarily test for existing infection.
Thomas
I’m not sure how I got it since I’m in a monogamous relationship and I don’t see anyone else. I use cocaine from time to time and my doctor said I could have been infected while sharing straws.
First tested on 13/03 after feeling a bit sick, I got positive on HBsAG and negative on the rest.
First test results
HBs Antigen Test: Positive
HBsAg Index 6.84 S/CO < 1.00
Anti-HBs Antibodies <2 mIU/mL Immunity > 10
Total Anti-HBc Antibodies Test: Negative
Anti-HBc Antibody Index 0.06 < 1.00
HBV DNA DETECTION AND QUANTIFICATION (TMA)
Reagent Kit: Aptima HBV Quant Assay - Hologic
< 10 IU/mL
No HBV DNA detection. Quantification range: 10 - 1,000,000,000 IU/mL (1 - 9 log)
HEPATITIS B SEROLOGY (Enzyme Immunoassay) #
Sample taken: 03/13/2025 Serum
Anti-HBc IgM antibody (Cobas Roche) Negative
<0.9 Threshold: 1.1
No serological evidence supporting acute hepatitis B infection.
Result to be interpreted based on the entire clinical and biological context.
I took a second test one month later on the 26/04 and got a negative result on HbsAg but haven’t developed antibodies (negative all over). Should I worry or am I in the clear ?
Second tests results
SERODIAGNOSIS OF VIRAL HEPATITIS B
(1) (Chemiluminescence)
03/11/25
HBs antigen test Negative
HBsAg index 0.44 S/CO < 1.00
Anti-HBs antibodies <2 mIU/mL immunity > 10 <2
03/11/25
Total anti-HBc antibody test Negative Negative
Anti-HBc antibody index 0.05 < 1.00 0.06
Interpretation: Absence of serological markers suggesting contact with the hepatitis B virus.
In case of suspected recent infection or a risk situation, these markers should be checked in 3 months. Vaccination may be offered according to the vaccination schedule.
Results should be compared with the clinical context. (HAS January 2017)
HEPATITIS B SEROLOGY (Enzyme Immunoassay) #
Sample: 04/25/2025 Serum 11:22 AM
Anti-HBc IgM Ab (Cobas Roche) Negative
<0.9 Threshold: 1.1
No serological evidence in favor of acute hepatitis B virus infection.
Result to be interpreted based on the entire clinical and biological context.
HBV DNA DETECTION AND QUANTIFICATION (TMA)
Reagent kit: Aptima HBV Quant Assay - Hologic
< 10 IU/ml
No HBV DNA detection.
Quantification range: 10 - 1,000,000,000 IU/ml (1 - 9 log)
Just wanted to know if I’m all good or not cleared yet from the acute infection.
Thank you in advance !
Hi @JeanGenie,
Welcome to the community. If I understand correctly, these two tests happened a month apart, right? If that is the case, I am not sure the results were accurate. Why? I’m unsure if you were infected and cleared it within a month. Plus, you still do not have any antibodies. This makes me believe that one of these results is false. I will recommend taking the test in 2 months with confirmation. If you test negative for HBV and still have no antibodies, the vaccination is the best way forward. Please be careful so you do not get exposed to other infections when sharing with others. Best, Bansah1
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I suspect I caught it in January. I had a big party and I didnt pay that much attention to my own comsuption.
I will definitely retake a test in two months. Thank you for your reply!
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Sure, lets see what the results are in two months. Sharing with others is a possible mode of HBV transmission and vaccination is the best protection against HBV. If your surface antigen and antibodies remains negative with no viral DNA, then you will need to get vaccinated as soon as possible. Take care and keep us posted. Thanks, Bansah1
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Dear @JeanGenie,
It may be possible that your original HBsAg test was a false-positive. I say this as all of your other HBV markers are negative, including anti-HBc which is present in cases of exposure, present, and past infection.
Agree with the previous points about repeating blood tests to work out what is happening, but if indeed all your markers remain negative, the general suggested recommendation is to be vaccinated so that you would be protected against any future exposure events.
Thomas
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Hello Hep B community! I’m a 30-year-old male diagnosed with Hepatitis B last December during a routine checkup. My initial lab results showed HBsAg reactive, HBV DNA 802 million, ALT 120 u/mL, HBsAb reactive and HBeAg reactive. After starting Truvada, my HBV DNA dropped to 21,000 IU/mL and ALT to 61 u/mL within four months. This journey has been tough, filled with fears about the future. Can anyone share tips on coping with the emotional aspects of living with Hep B?"
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Hello community,
Can anyone help me with my results.
Hep b Surface Antigen-Tested reactive
Hep b surface antibody-tested reactive >1000mIU/ML
Hep b Core antibody- non reactive.
I have had the hep b vaccine dose given to me twice.
Welcome @Shiro
I’m not an expert but someone with more
knowledge will answer your questions soon.
Blessings
It would be interesting to ask your doctor for a quantitative test for your surface antigen. You might be able to see if it’s low and on your way to a functional cure. I also am positive for both, the way it’s been explained to me is that there’s various mutations that the hbv virus can make and that the surface antibodies might mount a defense but it’s not enough to overcome the quantity of the surface antigen that is being produced.
Hi @Shiro,
Welcome to the community, and sorry about the late responses. Your results indicate that you tested positive for both HBsAg and HBsAb. While this is very rare, it is also challenging to tell whether the test for the surface antigen is a false positive. Have you had a viral load/HBV DNA test done? I also agree with @Albasil808 about getting a surface antigen quantitative done, as it will help provide a full picture of your condition. Getting either test done and maybe repeating the HBsAg test can help. Thanks, Bansah1
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Hi @ Shiro
According to your HBV profile, your anti HBc negative that means you had never exposed or infected with HBV. Your anti HBs > 1,000 mIU/ml which is very high and suggests that you have strong immunity against HBV . However, your HBsAg is positive that paradox with anti HBs positive, so the chances may be from false positive laboratory result for HBsAg like @ Bansah mentioned and the other may be from your HBV vaccine which contains HBsAg that can persists in blood circulation for about one month. So, if you get tested for HBsAg within 1 month after vaccination , your HBsAg test result may positive. I hope this may help you to understand your HBV profile.
chul_chan
Chulapong Chanta MD. Pediatrics
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Dear @ Shiro,
What kind of HBcAg antibody test did you have performed? Total (IgG + IgM) or IgM?
Hi @Shiro,
Welcome to the forum!
Yes, I agree with @availlant that you should check whether this is a IgM anti-HBc (which detects recent HBV exposure) or a total anti-HBc (which detects any previous HBV exposure) test.
It’d also be worthwhile to provide us with when you got the vaccination and when you got the blood test to address the point that @chul_chan has mentioned: the vaccine can also produce a positive HBsAg test.
Hope this helps,
Thomas
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Hello everyone!
I did my regular 6 monts check up and I wanted your thoughts on these results:
Note that I am not under any medication.
- My viral load was negative/undetected for the first time in 11 years (but the doctor ordered a retest).
- My ALT and ASAT level were normal (last time, 6 months ago, ALT were 80 with 46 being the normal threshold).
- HBs was positve
- Anti HBs was negative.
My doctor (GP) wanted to check if I cleared the virus and sent me to a hepatologist for further tests.
Unfortunately, this was not the case. Eveything was again normal in both tests (ALT, etc) but my viral load was a bit above 1000. Is this normal to have such different viral loads within ~3 weeks? (Note that this was the time in 3 years by viral load went above 1000).
Best,
Drew
Hi @Drew_rous
I would say from my knowledge that results can fluctuate but I’m not a doctor or medical professional.
Someone with more knowledge than me will help you soon.
Fantastic that you are undetectable
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Hi @Drew_rous,
I have not experienced that with my viral load. What I have experienced has been with my ALT and AST. I have had different numbers just a couple of days apart. I also think onetime, my results said HBV DNA was undetectable, and the next results said it was detectable. But I have not seen a change in the actual viral load numbers over a few weeks apart from testing. The best way is to get this test repeated again in 2 -3 months to see what the results are. I hope this helps, Bansah1
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