okay. thank you so much.
@Jack
That’s awesome news Jack. Lucky you.
Hello everyone!
I did my regular 6 monts check up and I wanted your thoughts on these results:
Note that I am not under any medication.
- My viral load is negative/undetected for the first time in 11 years (but the doctor ordered a retest).
- My ALT and ASAT level are normal (last time, 6 months ago, ALT were 80 with 46 being the normal threshold).
- HBs is positve
- Anti HBs is negative.
I am still waiting on some other results (Hep-Serologie)
What does that mean? Is there a chance of functional cure? Is there a chance of reactivation?
Best,
Drew
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Hi @Drew_rous,
Your results show that your HBV is becoming well-controlled, which is great. As indicated by normal ALT, AST, and undetectable viral load. Your immune system is doing a good job of controlling the disease.
Yes, you can achieve a functional cure depending on your surface antigen quantitative level. Remember that nothing is guaranteed, but it is possible. There is always a chance of reactivation due to other diseases, infections, weakened immune system, medications, etc.
Overall, your results show a controlled infection. Best, Bansah1
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Thank you very much for the response!
I have one more question. What does the undetectable viral load mean with respect to infecting others?
Best,
Drew
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Hi @Drew_rous,
That is a great question. Undetectable means that the amount of virus in your blood is too low to be measured by the test. It does not mean you do not have HBV. It only means that your virus is not multiplying or increasing in your blood as so they are unable to measure it with the test. With regards to infecting others, the chances are less likely. People are more contagious when the viral load is high. Low viral load means less inflammation of the liver, and a lower transmission/risk.
NOTE: This only applies to HBV, but you will remain exposed to other viruses or diseases. Safe practices are required for some things, especially those that are sexual. I hope this is helpful. Bansah1
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Hi Thomas,
Just recently received my blood test results. I don’t like what I see but also I don’t understand everything here. Can you please help me interpret please.
Thank you so much🙏
Hi @Q_Nguy,
Your results show a high viral load of 53.8 million and a slight increase in your ALT. I am not concerned much about your ALT, but your viral load is very high. Is this your first test? If so, I will say repeat in 3 months with AST and an ultrasound. Based on those results, you can discuss treatment options with your provider if the viral load remains high at that time. I will ask that you be careful and safe, as with this high viral load, you remain infectious or can infect others if exposed. Best, Bansah1
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Hi Bansah,
Thanks for responding. I am 46 years old, found out in early 2021 that I was likely been living my whole life with chronic hep B without even knowing it. In 2021 I felt very sick, ALT levels spiked and viral load was 6 figures. Since that happened, I am now being monitored by a hepatologist. I have yet to speak with the specialist regarding this recent blood work, I am nervous about these high levels.
Quoc N
Hi @Q_Nguy,
The way you found out is very similar to how many of us found out. In most people, HBV does not show any signs or symptoms, and by the time it does, it is always too late to intervene. I am glad you found out back in 2021. Is there any reason why you have not been monitored since 2021? If the viral load was 6 figures at that time, then it has increased. With all the extra information, I think it is appropriate to start treatment. Don’t be nervous, I understand the numbers are high, but I have seen some patients with higher numbers than yours. Please, speak with the specialist about treatment and what antiviral treatment options are available. I think starting treatment will help stop the viral replication and prevent further liver inflammation that could damage your liver. I hope you can see the specialist sooner for further conversation about this. Keep us posted, and know that you are not alone in this. Bansah1
2 Likes
Hi Basrah,
I should of added that I have been monitored since 2021. When I first showed symptoms, ALT and viral load was elevated and blood work after showed that ALT and viral have dropped to levels where my doctor said he was not concerned. The recent blood work seems concerning as my doctor called me, he has never called me to book appointments. I have always called myself to book appointments after 6 months blood work and ultrasound.
I also would like to include that I have cysts in my liver. Ultrasound found small cysts in 2021 witch have grown from 2mm to 10mm.
Thanks for all your help🙏
Quoc
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Hi @Q_Nguy,
Oh, I see. Thanks for the extra information. I think when you see the doctor treatment should be initiated since we don’t know how long since your last test the viral load and ALT have been up. I bet that call scared you. It’s good that you have a provider that understands your condition and is on top of things.
It’s common to find cysts but as the treatment continues it does stabilizes so those cysts don’t grow bigger. At least that has been in my case.
Best, Bansah1
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Thanks Bansah!
I will provide updates to this forum as soon as I have more information!
Quoc
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Thank you so much for sharing this @ThomasTu . It helps us to understand our test result better.
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Please I need an interpreter for my result I have been vaccinated for hapitte B since 2021 to 2022 including 3 does I have done 2 medical test for fitness and I was fit
This year I went for another blood test and doctor said I have a reactive hapitte B of the following hbsag reactive, hbsab reactive, hbeag non reactive, hbeab reactive and hbcab reactive and Noone could explain to me and I’m dying thinking on what to do am confused just don’t know what to do now please any help
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Dear @Anthony_Oscar_Kamara,
Welcome to the forum and thank you for sharing your story. I understand that it is very stressful at the moment.
Being HBsAg-positive means you have a current infection of hepatitis B. You may have had this before your vaccination, which would have had no effect if you already had it. Hepatitis B is a manageable condition that many other people on this forum (including myself) have and live with.
It is important that you keep monitoring to: 1) confirm these blood results accurately reflect your condition; 2) to understand your liver health; and 3) to determine if you would benefit from treatment or if it is OK to just keep monitoring your condition for now.
Hope this helps,
Thomas
3 Likes
Dr, am trying to do another test again but the country am currently is diffult to live with hapitte coz all test of it must knows by the government
Regarding my vaccination I did it 3yrs back even before my vaccination I want for a medical test which showed I am fit.
So that mean I was negative of it
Earlier this year I went home and doctor said I’m reactive of it. But like you said I will fight to redo the test again.
Hi @Anthony_Oscar_Kamara, I’m not sure about what the initial tests were and these do not necessarily test for existing infection.
Thomas
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I’m not sure how I got it since I’m in a monogamous relationship and I don’t see anyone else. I use cocaine from time to time and my doctor said I could have been infected while sharing straws.
First tested on 13/03 after feeling a bit sick, I got positive on HBsAG and negative on the rest.
First test results
HBs Antigen Test: Positive
HBsAg Index 6.84 S/CO < 1.00
Anti-HBs Antibodies <2 mIU/mL Immunity > 10
Total Anti-HBc Antibodies Test: Negative
Anti-HBc Antibody Index 0.06 < 1.00
HBV DNA DETECTION AND QUANTIFICATION (TMA)
Reagent Kit: Aptima HBV Quant Assay - Hologic
< 10 IU/mL
No HBV DNA detection. Quantification range: 10 - 1,000,000,000 IU/mL (1 - 9 log)
HEPATITIS B SEROLOGY (Enzyme Immunoassay) #
Sample taken: 03/13/2025 Serum
Anti-HBc IgM antibody (Cobas Roche) Negative
<0.9 Threshold: 1.1
No serological evidence supporting acute hepatitis B infection.
Result to be interpreted based on the entire clinical and biological context.
I took a second test one month later on the 26/04 and got a negative result on HbsAg but haven’t developed antibodies (negative all over). Should I worry or am I in the clear ?
Second tests results
SERODIAGNOSIS OF VIRAL HEPATITIS B
(1) (Chemiluminescence)
03/11/25
HBs antigen test Negative
HBsAg index 0.44 S/CO < 1.00
Anti-HBs antibodies <2 mIU/mL immunity > 10 <2
03/11/25
Total anti-HBc antibody test Negative Negative
Anti-HBc antibody index 0.05 < 1.00 0.06
Interpretation: Absence of serological markers suggesting contact with the hepatitis B virus.
In case of suspected recent infection or a risk situation, these markers should be checked in 3 months. Vaccination may be offered according to the vaccination schedule.
Results should be compared with the clinical context. (HAS January 2017)
HEPATITIS B SEROLOGY (Enzyme Immunoassay) #
Sample: 04/25/2025 Serum 11:22 AM
Anti-HBc IgM Ab (Cobas Roche) Negative
<0.9 Threshold: 1.1
No serological evidence in favor of acute hepatitis B virus infection.
Result to be interpreted based on the entire clinical and biological context.
HBV DNA DETECTION AND QUANTIFICATION (TMA)
Reagent kit: Aptima HBV Quant Assay - Hologic
< 10 IU/ml
No HBV DNA detection.
Quantification range: 10 - 1,000,000,000 IU/ml (1 - 9 log)
Just wanted to know if I’m all good or not cleared yet from the acute infection.
Thank you in advance !
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Hi @JeanGenie,
Welcome to the community. If I understand correctly, these two tests happened a month apart, right? If that is the case, I am not sure the results were accurate. Why? I’m unsure if you were infected and cleared it within a month. Plus, you still do not have any antibodies. This makes me believe that one of these results is false. I will recommend taking the test in 2 months with confirmation. If you test negative for HBV and still have no antibodies, the vaccination is the best way forward. Please be careful so you do not get exposed to other infections when sharing with others. Best, Bansah1
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