Please i need a response.
I tested positive for Hbsag positive. I was asked to go for HBV DNA detection Essay and it showed 3<10 IU/mL.
I was asked to get livolin forte.
Please I’m I on the right track
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Dear @tye,
Welcome to the forum. HBsAg positive suggests you are a carrier of hepatitis B, but your immune system appears to be controlling it well as you viral load is very very low (<10IU/mL). People with these results tend to be very stable and have low rates of disease progression.
The recommended course forward is to maintain monitoring (get blood tests every 6 months, and fibroscan) to see if your results change over time.
Thomas
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Thank you Doctor.
I should keep on with the drugs is what you are saying.
Dear @tye,
The most important part is maintaining monitoring.
We cannot make decisions about your medications on this forum (and indeed you shouldn’t take such advice from strangers on the internet). This is a decision to be made and conversation to be had with your health care provider.
Thomas
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Hello,
First of all, I would like to thank you for joining the community. I’ll say right away that a week ago I didn’t know that I would need support. I am writing on behalf of myself, but also on behalf of my husband.
We have been unsuccessfully trying to get offspring for several years. A month ago, we went to a clinic dealing with infertility treatment.
As you can guess, the first basic tests are all kinds of tests, including those for the presence of viruses. We have received the results and we have an appointment with a hepatologist this Saturday. However, this does not give me peace and here I send a request for interpretation of my husband’s results. The clinic said that we can return to the treatment of infertility with extracordic methods when the results are good.
I will add that about a year after my husband’s birth, his mother had hepatitis and has an anti-HBs gene present.
What should we know at the beginning of the struggle with this disease?
HBs - antygen HBs (WZW typu B) (V39) 5241,44 s/co obecny
HBc - p/c przeciw HBc total (WZW typu B) (V31)
6,14 s/co obecne
Albumina w surowicy (I09) 4,7 g/dL
Fosfataza alkaliczna (ALP) (L11) 90 U/L
Aminotransfereza asparaginianowa (AST) 28 U/L
Aminotransferaza alaninowa (ALT) (I17) 35 U/L
Gamma-glutamylotranspeptydaza (GGTP)
35 U/L
Bilirubina całkowita (I89) 0,76 mg/dL
Thanks in advanced for your support!
Anes
HBs - HBs antigen (Hepatitis B) (V39) 5241.44 s/co present
HBc - anti-HBc total (Hepatitis B) (V31) 6.14 s/co present
Serum albumin (I09) 4.7 g/dL
Alkaline phosphatase (ALP) (L11) 90 U/L
Aspartate aminotransferase (AST) 28 U/L
Alanine aminotransferase (ALT) (I17) 35 U/L
Gamma-glutamyl transpeptidase (GGTP) 35 U/L
Total bilirubin (I89) 0.76 mg/dL
Dear @Aneta_S,
Welcome to the forum and hope you get the support you need here. Some additional tests you might consider getting, include:
- HBV DNA (shows how much virus there is in the blood and is useful in knowing if antiviral treatment is recommended)
- HBeAg and anti-HBe (again, important in knowing if antiviral treatment is recommended)
- Fibroscan (gives you an idea of liver health).
Hope this helps,
Thomas
Hi @ThomasTu
May you please help me interpret these results. Does it mean l currently have an infection and it has not shown up yet in the tests or its a past infection
Hepatitis B Surface Ag
Not Detected
N - Normal, applies only to non-numeric values.
07/10/2024 13:48
Hepatitis B Surface Ab
<10
IU/L
N - Normal, applies only to non-numeric values.
Hepatitis B Core Ab (Total)
EQUIVOCAL
Dear @availlant @ThomasTu
i did the test again for hbv dna, hbsag(iu/ml), hbcrag , hbeag,
1, hbv dna is now 154iu/ml
2, hbeag continue as seroconverted
3, hbcrag <3log10 iu/ml
4, hbsag is 174iu/ml
and my doctor told me not to start treatment and i never been on treatment also. but i have also follow up with private doctor and suggested me to be on vitamin E 400mg for 3 month to see.
Hi @Bae,
These results are consistent with not being exposed to Hep B and not being vaccinated. The general recommended action would be to get vaccinated so that you are protected from future exposure events.
Hi @lemlem,
Not treating is consistent with current treatment guidelines: your viral load is so low that any additional benefit from antiviral therapy (at least from a liver disease progression perspective) is not detectable in current clinical trials.
Hope this helps,
Thomas
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Hi @ThomasTu
Thank you for the reply. I am now less stressed. I was worried about the Hepatitis core test (total) being equivocal , what are the chances that if l send a repeat sample l might get a positive. What causes such a test to come back equivocal?
Regards
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thank you @ThomasTu well understand.
2 Likes
Hello,
Please let me understand the results.
HBsAg - positive
HBsAb - 0.0 (not immune)
Hepatitis B virus DNA (HBV) - not detected
Uhmm? How is it not detected if I’m diagnosed with it?
Additionally, Model End stage Liver Disease (MELD) score is 9.1
I have also elevated following enzymes:
ALP - 153 units (norm is 30-120)
ALT is ok, 31 units (norm 7-40)
GGT is ok, 20 units (norm is less than 64)
Also,
Elevated total bilirubin: 1.4 mg/dL (norm is 0.2-1.3)
Elevated indirect total bilirubin 0.96 mg/dL (norm 0.1-0.8)
Direct bilirubine is on the border of the norm: 0.44 mg/dL (norm is up to 0.45). And so is creatinine: 1.16 mg/dL (norm between 0.72-1.17)
I’ve been on TDF since April this year. Waiting for the info about viral load. This one doesn’t say.
So, I posted a while ago that I had some weird results, and I’ll just post them here. Despite being vaccinated 20 years ago, my HbsAb a few months ago was around 1 mIU/ml - the test said I basically wasn’t protected. They didn’t actually test HbsAg for some reason, even though they thought they did.
I knew I had another test to do, but I decided I would use the opportunity before hand to get a booster. So I got one shot of the engerix-b vaccine. At that point they wanted to test me, but I didn’t want to wait a whole month to test again as the doctor was waiting for it. So I waited 18 days, which seems like the minimum from a few studies they did.
On the retest, 18 days after my vaccination, the results were:
HbsAg - Non reactive
Hbs Core Ab (IgG + IgM) - Non reactive
HbsAb - 374 mIU/ml
So it looks like I don’t have hepatitis B I guess, which is good. My question is with regards to the antibodies, I know 10 mIU/ml is the threshold, but I suspect since this was only on day 18 that the antibodies will drop fast. Do people recommend I do another shot at the one month mark, or possibly one more at the six month mark (I completed a series in 2004)? I just want to make sure I’m protected for the last of my adult life at this point.
Thanks
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Hello @Arb
Your results are only slightly over the limits.
This is normal.
Others will help answer your questions soon.
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Hi @Arb,
@Caraline is right about some of your results being a little high. You do have hepatitis B, and the HBV DNA not detected means that the virus in your blood is low to be measured. Note that HBV DNA and Viral load tests can be used interchangeably. Which is what you want. The higher the viral load, the risk of liver damage increases. Many patients on treatment have undetectable HBV DNA. The liver panel, ALT looks normal but I don’t see AST. I am not sure what the other enzymes indicate. Since the other results are a fraction high, I will say keep your eye on it. TDF is working and keeping your viral load down which is good. Keep up with your treatment and monitoring. Best, Bansah1.
2 Likes
Hi @Stargazer6138,
Congratulations on your results. Your high antibody levels are a good sign that you’ll be protected for a long time yet. They are not likely to drop significantly in the short term. Regardless of your antibody levels, you have also now developed the memory B cells so that your body can respond extra quickly in case you are exposed in the future.
Hi @arb,
Your undetectable HBV DNA load is expected as you are on antiviral treatment. This is a good sign that the antivirals are working!
Hope this helps,
Thomas
2 Likes
Thanks Thomas. So with an antibody level like I have of 374, do you think I should do one more booster, or is that enough for the future?
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Dear @Stargazer6138,
I am not sure, if you have started a booster series it’s usually recommended to complete that course. If you have completed the course, then there is no necessity to have additional boosters.
Thomas