EXPLAINER: Lab results and their interpretation

Hi @Lovely,
Welcome to the platform. Your ALT/AST is high. The standard range varies by laboratory, for ALT 7-55 U/L and AST 8-48 U/L. As you can see your numbers of 140 and 87 are over the standard range. I will agree with you, but talk to your provider about this. Start from there and then if that result(s) is normal then you can probe other sources for this issue with your provider. Best, Bansah1.

Dear @Lovely,

You have no evidence of an ongoing HBV infection in this qualitative screen (HBsAg = not detected), but you do have serological evidence of a past infection (HBcAg antibody = detected; the IgM just says that the HBcAg antibody was not initially stimulated within the last month or 2). The ALT/AST values seem a bit high, but the upper limit of normal can vary from place to place and assay to assay, so you’ll need your doctor’s help to diagnose that. Loss of anti-HBs could contribute to a rise in ALT/AST if HBV were reinfecting your liver, but the lack of HBsAg in your blood makes that quite unlikely. I have no idea how this may be related to your Diabietes, but I am an HBV scientist rather than a physician.

Overall, I encourage you to speak with your doctor. S/he will be able to interpret these results in context of your full medical history and give you the guidance you seek.

I wish you the very best.

John Tavis

Dear @Lovely,

Welcome to the forum and hope you find this forum useful!

Yes, agree that your ALTs are relatively high. Given that you have been recently diagnosed with diabetes, it may be worthwhile to consider Steatotic Liver Disease (formerly known as fatty liver disease). Have a talk to your doctor about this and they should be able to do some tests to determine if this is the case.

Thomas

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Thanks so much for sharing your opinion!

Thanks @ThomasTu . I ll need to talk to a specialist

Thanks for your input :pray:

Hi all,

Could one of our lovely @ScienceExperts please help me in interpreting my results?

I had to rush on my lunch break to grab them and I didn’t want to pressure my Korean doctor to explain them quickly for me.

Previous results: all I know is I have a chronic infection but my liver function test on December showed no inflammation and normal results. My doctor did not do a full HBV DNA PCR at the time.

Also, please excuse my crusty nail, I’ve been holding out on getting them done until just before I go on vacation next week :sweat_smile:

TIA ^^


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Hi @EH1999 ,

Your liver function is normal and your HBV DNA (viral activity) is not detectable. Are you taking antiviral therapy?

Best regards,

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Thank you for you response @availlant

Sorry, not detectable? I’m not taking any antivirals, I never have. What does that mean?

Many thanks :slight_smile:

Hello, i cant read korean but does that say hbsag negative? :+1:t2:

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Yeah, it does. Don’t really know what that means though

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Pls explain this HBV profile results given that I had unprotected sex august last year and 2016 which could lead to this infection

hbsag negative usually means you cleared it, was you hbsag positive before?

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Dear @EH1999,

Both your HBV DNA and HBsAg being undetectable is a good sign that your immune system is clearing the HBV infected cells from your liver successfully. It is recommended that you maintain monitoring to make sure that these remain low.

Hi @CSKAY,

This is not a standard profile (as it does not match any of the patterns beneath the results). It may be worth repeating these tests to make sure none are false-positives or false-negatives.

Thomas

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@ThomasTu thank you for your response. I’m sorry, I’m trying to wrap my head around this. Does this mean that I’m on my way to being “functionally” cured?

Yes, this is a reasonable interpretation of the results. You would need to make sure that this is not a temporary reduction and it is long-lasting, so you’d need a follow up test. But it is promising news, congratulations!

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Oh wow! I can’t quite comprehend it right now but that’s amazing! Thank you for taking the time to explain :slight_smile:

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@availant I think this is a subject that needs more discussion in the group. And thank you for sharing

Hello @ethan
What is your age?
I’m not a medical expert, but those symptoms you described could be anything.
I have lines like that, and I think they’re from old age, ageing.
Are you in contact with the doctor?
Blessings, Caroline.

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Hi hep B community I was diagnosed with hepatitis B on 7 July 2023 and the doctor said they can put me on treatment unless it’s they see the viral load results which I did on 9 July and the viral load was 825.0 IU/ml. Can this be acute or chronic and can I transmit the virus saliva or anybody fluid