Hello,
Thanks, @ThomasTu and @Bansah1, for the info and advice
May I also ask how often I should measure my antibodies, given the fact I lost my initial ones from the birth series vaccination (to value of 0.5UI/ml) and how quickly (on average) they will reappear. 1-2 weeks maybe?
Hi @StevenS,
If you check in the next month or so and it is back to normal or higher, there is no need to check again. Maybe after a number of years you can recheck again. These antibodies could last longer. If your initial dose was as a child and now as an adult you need a booster, that should give you some idea on how long it takes to lose it. I hope this helps. Bansah1
Hi @StevenS,
Such antibody levels generally last for years to decades. It would not be something I would worry about continually checking unless you are in a high-risk exposure environment. But if it gives you peace of mind, it can be a test that is added to an annual health check.
TT
Hello,
I understand. May I ask if a positive anti-HBs is enough to tell if everything is fine as I will go in 3 weeks for blood screening?
And also, if the answer to the upper question is “no”, may I go for the final checkup only with the HBsAg check and not the full test panel, as it is rather expensive for me?
Hi @StevenS,
Yes, not just testing for HBsAb, but also get the antibodies quantitative or measured. This will show the antibody level after your booster. You want a number greater than 10 mIU/mL. I don’t think you need a HBsAg test, all you need is HBsAb. Best, Bansah1
Hello again,
My local health center recommended full revaccination with 3 doses
May I ask is it safe for the vaccination process to take Inosine acedoben dimepranol (immunomodulatory drug) during the course of HBV vaccination. Prescribed for cold and herpes in the nose
Can the intake of the medicine affect the antibodies in negative way?
Hi @StevenS,
I am not familiar with this medicine, but the question will be whether this medicine affects one’s immune system in any way? If the answer to it being an immune suppressant is yes, then I will avoid it while getting the vaccine. But if you need that medicine now, then go ahead and take it, get the vaccine a month or two after it has left your system. Please, have a discussion with your doctor about this. They will know what will work best for your situation. Best, Bansah1
It does not suppress the immune system but rather on the contrary, yet again I am not sure if that could influence my antibodies
Speak to the prescriber about your concerns to learn whether they are valid or not. Thanks
Perhaps some of our @PharmacyExperts can provide some more expertise as well.
My reading about this seems to show that very little research has been done on this. All I could find was in broiler chickens, where administering this drug along with vaccination increased the vaccine efficacy - Evaluation of Inosine-Acedoben-Dimepranol as an immunomodulator in broiler chicks vaccinated with infectious bronchitis virus vaccine.
But there’s also variable evidence for its antiviral effectiveness in patients - Failure of oral inosiplex treatment of recurrent herpes simplex virus infections - PubMed and Efficacy and Safety of Inosine Pranobex in COVID-19 Patients: A Multicenter Phase 3 Randomized Double-Blind, Placebo-Controlled Trial - PubMed
My understanding is that this compound is quickly metabolised and excreted by the body anyway, so likely not necessary to be off it for months to clear it.
Hope this helps,
Thomas
Hello
Thanks @ThomasTu. There is probably a misunderstanding because I am 10 days after my second dose of the vaccine( full revaccination recommended by the local health center). I mean the vaccination schedule is already started. I finish with the medicine today
Oh, and one more thing. If there are 1-2 drops of blood on a spoon, fork, or knife. Can it be washed just with detergent and water, or is bleach strongly needed?
Asking because there is an elderly non-vaccinated person(refusing the vaccine) in the household with autoimmune PBC (some variety of cirrhosis)
Thanks again for all @ThomasTu
In fact, I have 1 hour free per day, may I help in return for your answering, in some way, here in the forum?
Hi @StevenS,
Apologies about the misunderstanding. I guess you will find out if it affected the vaccination efficacy when you test for antibody levels.
To answer your other question, detergent and water are very effective in inactivating the virus, as mentioned in other threads Inactivating Hep B
Hope this helps,
Thomas