Nucleic acid polymers (NAPs): targeting subviral particles to achieve HBV functional cure

Dear Mr.@availlant

this is stefano (stef2011) from medhelp hbv community, i am very glad this community is very active…just an idea:
i remember private clinics in germany have very permissive laws for experimental treatments, would it be possible to get NAPs +Thymosin+tdf/taf or etv treatment there if the patient pays all the expenses?HDV has no cure but also HBV has no cure (we can just manage damage) and TDF/TAF are not totally free from side effects for all patients longterm (10-20 years of treatment can damage kidneys/bones and mitochondria)…i mean we cannot take tdf/taf for life.what do you think?after we see naps are very safe on decompendated cirrhosis maybe we can open a door for hbv infected patients that want to stop nucs but avoid relapse/fulminant hepatitis
thank you

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