Having children and Hepatitis B

Yes I agree with the other specialists that you should continue on your Tenofovir during pregnancy to reduce the risk of transmitting hepatitis B to your baby. Tenofovir has been taken during pregnancy by many women worldwide and it is thought to be very safe.
All the best!
Mark Douglas (Infectious Diseases Specialist)

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Thank you all for your responses. I will be staying on the Vemlidy and registering with them so they’ll have more info regarding Vemlidy and pregnancy.

Christy

Dear Christy, it’s wonderful that so many doctors responded to your question about vemlidy and your pregnancy. But I want to reinforce what Dr. John Tavis wrote about making sure that your newborn receives the first dose of the hep b vaccine in the delivery room. And if possible, 1 dose of the HBIG (hep b immune globulin). It is very important to protect your newborn immediately after birth to prevent a possible infection from the hep b virus. You only have one chance. So that’s why the Hepatitis B Foundation recommends making sure that the 1st dose of hep b vaccine and 1 dose of HBIG is available in the delivery room so your newborn receives both shots soon after birth. Making sure of this AND taking vemlidy for the entire 9 months of pregnancy to keep your viral load as low as possible will definitely eliminate the risk of possible transmission.

Good luck with the pregnancy and keep us posted on how things go. And of course we’d all love to know whether you’re having a boy or a girl?!!! Always, Joan

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It’s still way to early to know if it’s a boy or girl. But my first ultrasound is on July 30th and I’ll know then if it’s just one or multiples. :slightly_smiling_face: I’ll let y’all know when I find out. Thanks so much for all the replies!

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Thanks Sonshine4u - we’ll be eager to hear what you learn. The first ultrasound is so exciting!!! Always, Joan

Hi everyone,

After completing the three shots of HBV (GenevacB) vaccine last year. My wife’s antihbs titre was 71miu/ml and 88miu/ml at 4 and 6 weeks respectively. Presently she is pregnant ( first trimester). Please, does pregnancy compromise or reduce the body’s antihbs titre? if so, is it safe that we continually engage in unprotected sex this period. Since I am still HBV positive.

Thanks and regards

Hi @Chisomcharles198,

This looks like your wife has responded well to the vaccination and is protected against HBV infection. I am not aware of any studies showing anti-HBs antibody titres going down during pregnancy, though this can perhaps be answered by one of our @HealthExperts.

Thomas

I’m not aware of any study showing that anti-HBs titer decline during pregnancy. Even if this is the case, I do not think this would a major problem, cellular immunity will be likely to play also a major role.

PL

Prof. Pietro Lampertico, MD, PhD

Full Professor of Gastroenterology

Head of Gastroenterology and Hepatology Division

Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico

University of Milan

Via Francesco Sforza 35

20122- Milan

Italy

Phone +390255035432

Fax +390250320410

Email pietro.lampertico@unimi.it

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Thank you Dr. Thomas for your response. I am so grateful

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Thank you Prof. Pietro, I am grateful for your response.

Hello everyone,

I hope you all are doing well!

I am an old member of the group but I haven’t been active for a while. I’m just trying to support and navigate with my husband who is a chronic Hep B carrier :blush:

I have a question I wanted to ask, or hope to get some answers to put my mind at ease. My husband and I plan to try to conceive next year. And I read up online (bad habit, I know, the internet always scares me), about how chronic hep B can negatively affect males fertility. This is something I haven’t came across before so I’m a little sad. I just wanted to know if the chance for us to have children is significantly decreased or if there is still hope. Thank you so much!!

Hi @Tran-ng,

Thanks for the question. I think when you look over a large population, the incidence of infertility is slightly higher in people with Hep B and sperm motility is slightly lower. I don’t think much is known about why this is.

On an individual level though, there is high variation. So just because you husband has hep B doesn’t mean you won’t be able to conceive.

TT

I have two kids - the first one was conceived when I was not on the antiviral; the second was conceived when I was on the antiviral.

Good luck! I wish someone told me how much work it is to raise kids, he he!

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Thank you Thomas for taking your time to answer my question. I’m very grateful for this community :blush:

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Thank you @mantana, you helped put my mind at ease. And yes I have been told lots of times to beware that having kids will change your life forever :joy: They are definitely not an easy job!

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Hi regarding this question. I am positive but my wife is negative and vacinated. She is pregnant. What can she do to protect our child? The same 24hrs vaccination rules apply?

Hi Labu,

If your wife is negative, then the risk of transmission at birth is quite low. But it is highly recommended that your newborn is vaccinated against HBV so that they are protected.

Thomas

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If my wife has been vaccinated,and her hbsab level is greater than 10.Do we still need to be checking her hbsab level Everytime before we have unprotected sex?
@ThomasTu @availlant @john.tavis @everyone

Dear @Godsown ,

HBV vaccination has a very long lasting protective effect and levels of HBsAb > 10 mIU/mL are indicative that this protection is in place for your wife. You do not need to check her HBsAb level.

Best regards,

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That’s it’s lifelong right? she’s protected?