EXPLAINER: Lab results and their interpretation

I feel the same symptoms, weight loss, itching, cracking in my joints.
I was tested for hepatitis b one year after exposure:
HBs ag-negative
Anti HBs-negative
Anti HBc total-negative
However, I see that AI searches indicate a possible infection despite the negative results.

@Vhuthu

I think that is a good decision.

I know it can be scary. We are here for you.

And want to help in any way we can,

Just let us know.

Have a look around some of the topics of diets, exercise, health. To help

Keep your liver in tip top condition :smiling_face_with_three_hearts:

Nutrition and Dieting in Chronic Hep B

Stress

Effect of alcohol to the hepatitis b patients

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I been on and off this forum for the last year. If you have access to Claude or chatGPT on your phone/tablet/computer, it’s is another way to analyze or get some research on your test results. It’s is advised that you use caution loading up your medical records.

For me, I been using it. Don’t think someone is going to knock on my door for copying and pasting my blood work and reading of ultra sounds of the liver. lol

Found out the FIB-4 score is calculated as: (age x AST(u/l))/(ALT(u/l) x platelets(10^6/l)). Just FYI.

Hopefully everyone is doing well!

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Hi @Marko_Ortiz,

This does highlight the weaknesses of AI searches - they can just reinforce our assumptions. This profile is completely consistent with never having been exposed to Hepatitis B. For peace of mind, I would suggest you consider vaccination - this will induce protective antibodies so that you will be protected against any future exposures.

Thomas

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Thanks Thomas. I will certainly get vaccinated. Thanks again for the advice and help. I wish you all the best.

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Hello everyone.

Would you please help me with some advice/reassurance on this? I didn’t want to look online intentionally, as I don’t want to worry.

My husband was diagnosed with chronic Hep B in November (he thinks he’s got it as a child, from his father,who is also a carrier). After tests,I was negative and I started the vaccination. I’ve done already the second one but I started to worry a bit and I keep thinking of this…They booked me for one vaccination per month. I’ve completed already round one and two. However…how safe is to have such short periods of time between the vaccinations?

Maybe a bit too late to ask this question, but still good to know.

Thank you so much.

Hope

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Hi @Hope2025,
For the 2-shot series, those are given a month apart. The 3-shot series is at 0, 1, and 6 months. I am not sure which series you are following, but it seems to be right. These schedules are safe. Best, Bansah1

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Well…I am doing a three series of vaccination and each one is one month apart. So they booked me for the third one only one month after the second….

Thank you for your reply.

I feel now that maybe such a short period between all three vaccinations is not ok…

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The 3 series should be at 0, 1, and 6 months. I am unsure why you are scheduled for the 3rd shot only a month after the second dose. Bring this to the attention of your doctor or where you are receiving your vaccination so they can explain why the different routine for you and not following the recommended process.

Let’s know how it goes. Bansah1

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Thank you very much for your reply. Me neither…. Let’s hope I will find out and they will change the date.

What would de consequences be, from medical point of view, if all three vaccinations are taken only a month apart?

Just wondering….

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You are welcome. I doubt anything will happen; the intervals are based on what was found to be effective during the clinical trials for the vaccine. 2 shots in the 3-series provide about 70-75% protection, and the 3rd shot increases it to above 90%. Great question, I don’t have the answer.

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Hi @Hope2025,

Great to see you. Please note that there are different timelines for accelerated dosing (see here for the Australian ones - https://immunisationhandbook.health.gov.au/contents/vaccine-preventable-diseases/hepatitis-b). My understanding is that the first few doses will provide protection at least in the short term and the third is meant to lock it in place for long-term memory-based protection. So it’s unlikely anything bad will happen based on the timing of the third vaccination - the Hep B vaccine is one of the safest ones there are.

Thomas

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Thank you so much for the reassurance,Thomas. I didn’t have time to enquire about the third vaccination as it is very difficult to juggle a full time job and making time for phone calls. Getting in touch with your GP/ surgery is a very complicated matter now in England (this is where I live). I will go for my third vaccination as booked by the nurse and I will ask then why I only had one month apart between all three doses. However it is quite unlikely she can do anything about that.

Thank you again.

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Hows you now and how you feel with it

Hi Hope, no worries it’s just super fast scheme to protect you : 0-7-21 days and booster after one year … my wife got it the same way as she is negative and I’m positive unfortunately… after 3rd shot she got full protection as per blood result. Later I’ll introduce myself , for a moment I’m busy for a next few weeks. Good luck !

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Hi Gelo,

Thank you very much for your reply . It is very encouraging to hear from people with similar experiences. I am due to have the third dose of the vaccine tomorrow.

Hope

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Great to hear @Hope2025, hope it went well for you!

TT

Hi Lads,

Theirs is two quantity HBV DNA tests, one done in March and one done in July… should be checked every 6 months , however I’m going by end of September. So far no any treatment applied for me. Fibrobscan F-1, ALT,AST, GGT normal, straight bilirubin a bit higher. Will see what doctor will say next visit.

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Hello,

Below are my lab results. I visited the doctor for a different purpose, I was H pylori positive and during the routine blood tests i noticed my ALT and AST high and did my detailed test and i was Hep B positive. never had any symptoms in the past or i ignored it. I am 47 years old male.

ALT REDUCED FROM 500 to 360 to 235 (1st test done on June 30th, follow up July 07th and 2 days before again)

AST REDUCED FROM 360 to 230 to 155

BILRUBIN TOTAL 1.1

HEP BE ANTIBODY REACTIVE

HEP B CORE TOTAL AB REACTIVE

HEP B SURFACE ANTIBODY NON REACTIVE

HEP B SURFACE AB QUANTITATIVE <8.0

HBSAG REACTIVE (1284 READING WHEN I DID 3 WEEKS AGO)

HEP B CORE ANTIBODY IGM REACTIVE

HBV DNA COUNT WAS 33.8 MILLION 3 WEEKS AGO

Liver fibro scan also showed 14.2 KPA 3 weeks ago.

My doctor was still not sure if it is acute or chronic, he started me on tenvir af 25 mg keeping my HBV dna load which was taken 3 weeks before.

any interpretations from anyone, please advice!

I think this is likely acute, given the positive core IgM. If you don’t have any symptoms, I think the best thing to do would be to retest in 6 months. No need to test more often, unless you have any liver-related symptoms. Crossing my fingers for you that you will be able to clear it!

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